Emerging therapies against infections with Pseudomonas aeruginosa

Acute Pseudomonas aeruginosa Lung Infections

Pseudomonas aeruginosa infections and HIV

1 Craib KJP, Meddings DR, Strathdee SA, et al. Rectal gonorrhoea as an independent risk factor for HIV in a cohort of homosexual men. Genitourin Med 1995;71:150-4. 2 Mertens TE, Hayes RJ, Smith PG. Epidemiological methods to study the interaction between HIV infection and other sexually transmitted diseases. AIDS 1990; 4:57-65. 3 Laga M, Mamadou TE, Bure A. Interrelationship of sexually transmi...

Bactericidal Effect against Pseudomonas Aeruginosa

Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Department of Pathology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Central Laboratory, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Department of Microbiology, Kyoto University Graduate of Medicine, Kyoto, Japan Professor emeritus, Nagasaki Uni...

Novel antibiotic combinations against infections with almost completely resistant Pseudomonas aeruginosa and Acinetobacter species.

For infections with antibiotic-susceptible strains of Pseudomonas aeruginosa, most studies have suggested that combination therapy, usually with a beta -lactam antibiotic plus an aminoglycoside, is preferable for patients with bacteremia and neutropenia. Against infections with Pseudomonas aeruginosa or Acinetobacter baumannii isolates that are resistant to all antibiotics except the polymyxins...

Phage therapy is highly effective against chronic lung infections with Pseudomonas aeruginosa

With an increase in cases of multidrug-resistant Pseudomonas aeruginosa, alternative and adjunct treatments are needed, leading to renewed interest in bacteriophage therapy. There have been few clinically relevant studies of phage therapy against chronic lung infections. Using a novel murine model that uses a natural respiratory inhalation route of infection, we show that phage therapy is an ef...